CHEMBL3318850


SMILES O=C(CCc1cn(CCCCCCCCCCn2cc(CCC(=O)OC3(c4ccc(Cl)cc4)CCN(CCCC(=O)c4ccc(F)cc4)CC3)nn2)nn1)OC1(c2ccc(Cl)cc2)CCN(CCCC(=O)c2ccc(F)cc2)CC1
InChIKey ZJQBHEYWXVCZGD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 14
Hydrogen bond donors 0
Rotatable bonds 31
Molecular weight (Da) 1134.5

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 7.07 7.07 7.07 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.05 7.05 7.05 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.23 8.23 8.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.27 8.29 8.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database