CHEMBL315864


SMILES Oc1nc2c(N3CCN(Cc4ccccc4)CC3)cccc2[nH]1
InChIKey MKJHGVZTPBBKML-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 308.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 7.06 7.7 8.38 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.84 7.84 7.84 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.25 7.25 7.25 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.06 7.06 7.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database