CHEMBL3342862


SMILES COc1ccccc1N1CCN(CC2COC3(CCN(C(=O)C4CCCCC4)CC3)O2)CC1
InChIKey OKPOTQGIJMVOCK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 457.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.96 6.96 6.96 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.4 7.4 7.4 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.51 7.51 7.51 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.69 7.69 7.69 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database