CHEMBL321860


SMILES C/N=C(\NC#N)NC[C@H]1CC[C@H](c2c[nH]cn2)O1
InChIKey CCOQWVUQXNRKKP-PSASIEDQSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 3
Molecular weight (Da) 248.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.9 6.9 6.9 ChEMBL
H3 HRH3 Human Histamine A pKi 5.66 5.67 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.1 7.11 7.11 ChEMBL
H3 HRH3 Human Histamine A pEC50 5.5 5.5 5.5 ChEMBL