CHEMBL3233432


SMILES O=C(CCCN1CC[C@H]2[C@@H](C1)c1cccc3c1N2CCO3)c1ccc(F)cc1
InChIKey DLXKEWOEEPMPHX-PMACEKPBSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.98 6.98 6.98 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.39 7.39 7.39 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.5 6.5 6.5 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.58 6.58 6.58 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.05 9.05 9.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.88 5.88 5.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database