CHEMBL3403343


SMILES Cc1ccc(S(=O)(=O)c2cnc3ccc(F)cc3c2SCc2ccc(Cl)cc2)cc1
InChIKey SJMSRWIGJKIMDC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 457.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 4.9 4.9 4.9 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.19 5.19 5.19 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.93 4.93 4.93 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.51 4.51 4.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database