GproteinDb

CP55940

Agent/drug
Bioactivity

CP55940

SMILES	CCCCCCC(C)(C)c1ccc([C@@H]2C[C@H](O)CC[C@H]2CCCO)c(O)c1
InChIKey	YNZFFALZMRAPHQ-SYYKKAFVSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	3
Rotatable bonds	10
Molecular weight (Da)	376.3

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Guide To Pharmacology GPCRdb
Structure pdb	6KQI 7WV9 7FEE 8GUR 7V3Z
Ligand site mutations	CB₂

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Human	Cannabinoid	A	pKi	8.30	8.75	9.20	Guide to Pharmacology
CB₁	CNR1	Human	Cannabinoid	A	pKd	8.50	8.95	9.40	Guide to Pharmacology
CB₁	CNR1	Mouse	Cannabinoid	A	pKi	8.82	9.02	9.21	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pKi	7.89	8.89	9.57	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pKd	9.30	9.30	9.30	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	8.60	8.90	9.20	Guide to Pharmacology
CB₂	CNR2	Human	Cannabinoid	A	pKd	8.10	8.90	9.70	Guide to Pharmacology
CB₂	CNR2	Mouse	Cannabinoid	A	pKi	8.96	8.96	8.96	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKi	7.47	8.80	9.82	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pKd	9.23	9.23	9.23	ChEMBL

Showing 1 to 10 of 10 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CB₁	CNR1	Mouse	Cannabinoid	A	pEC50	7.38	7.38	7.38	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pIC50	7.56	8.87	9.89	ChEMBL
CB₁	CNR1	Human	Cannabinoid	A	pEC50	6.80	8.31	9.59	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pEC50	6.25	8.15	9.46	ChEMBL
CB₂	CNR2	Human	Cannabinoid	A	pIC50	8.08	8.79	9.09	ChEMBL
CB₂	CNR2	Rat	Cannabinoid	A	pEC50	9.47	9.47	9.47	ChEMBL
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pIC50	5.22	5.22	5.22	ChEMBL
GPR18	GPR18	Human	GPR18, GPR55 and GPR119	A	pEC50	5.22	5.22	5.22	ChEMBL
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	8.30	8.30	8.30	Guide to Pharmacology
GPR55	GPR55	Human	GPR18, GPR55 and GPR119	A	pEC50	5.79	5.79	5.79	ChEMBL
NPS	NPSR1	Human	Neuropeptide S	A	Potency	4.90	4.90	4.90	ChEMBL
TSH	TSHR	Human	Glycoprotein hormone	A	Potency	5.20	5.20	5.20	ChEMBL

Showing 1 to 12 of 12 entries

CP55940

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Guide To Pharmacology GPCRdb
Structure pdb	6KQI 7WV9 7FEE 8GUR 7V3Z
Ligand site mutations	CB₂

Compound is not listed as a drug.