GproteinDb

BERLEX COMPOUND

Agent/drug
Bioactivity

BERLEX COMPOUND

SMILES	N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1
InChIKey	MEEJEEVTIVAOJP-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	444.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCR1	CCR1	Human	Chemokine	A	pKi	7.28	7.28	7.28	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

CCR1	CCR1	Mouse	Chemokine	A	pIC50	5.30	5.30	5.30	ChEMBL
CCR1	CCR1	Human	Chemokine	A	pIC50	5.60	6.37	7.32	ChEMBL
CCR3	CCR3	Human	Chemokine	A	pIC50	5.05	5.05	5.05	ChEMBL
US28	US28	strain AD169	Unclassified	A	pIC50	5.03	5.03	5.03	ChEMBL
US28	US28	strain AD169	Unclassified	A	pEC50	5.34	5.40	5.50	ChEMBL

Showing 1 to 5 of 5 entries

BERLEX COMPOUND

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Clinical Trials

Phase I 0

Phase II 0

Phase III 0

Approved No

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.