CHEMBL347290


SMILES COc1cccc(C(=O)NCCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1
InChIKey SPVJCKMDCFPHSX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.52 8.52 8.52 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.1 7.1 7.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.81 5.81 5.81 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database