CHEMBL332154


SMILES O=c1ccc2ccc(CNCCNc3ccccc3)cc2o1
InChIKey RNNKCHJUBXFBQB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 294.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pKi 5.43 5.43 5.43 ChEMBL
α2A ADA2A Rat Adrenoceptors A pKi 5.57 5.57 5.57 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.24 8.24 8.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.37 6.37 6.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 8.89 8.89 8.89 ChEMBL