CHEMBL3321789


SMILES OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCCOc1ccc(F)cc1
InChIKey AWIYLVWAILOVMX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 8.39 8.39 8.39 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.05 6.05 6.05 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.38 6.38 6.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.66 7.66 7.66 ChEMBL
H1 HRH1 Human Histamine A pKi 5.38 5.38 5.38 ChEMBL
D4 DRD4 Rat Dopamine A pKi 7.31 7.31 7.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database