4-methylhistamine


SMILES Cc1c(CCN)nc[nH]1
InChIKey UGYXPZQILZRKJJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 125.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.3 7.75 8.2 Guide to Pharmacology
H2 HRH2 Human Histamine A pKi 5.1 5.1 5.1 ChEMBL
H3 HRH3 Human Histamine A pKi 5.2 5.2 5.2 ChEMBL
H4 HRH4 Human Histamine A pKi 7.3 7.3 7.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Rat Histamine A pEC50 5.6 5.6 5.6 ChEMBL
H1 HRH1 Human Histamine A pEC50 4.8 4.8 4.8 ChEMBL
H2 HRH2 Human Histamine A pEC50 5.5 5.52 5.54 ChEMBL
H3 HRH3 Human Histamine A pEC50 4.91 4.91 4.91 ChEMBL
H4 HRH4 Human Histamine A pEC50 7.15 7.35 7.5 ChEMBL
H4 HRH4 Mouse Histamine A pEC50 5.8 5.8 5.8 ChEMBL