CHEMBL3342863


SMILES COc1ccccc1N1CCN(CC2COC3(CCN(C(=O)C4CCCN4)CC3)O2)CC1
InChIKey PCMIZIOZMQFVGQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 444.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.8 6.8 6.8 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.57 7.57 7.57 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.93 7.93 7.93 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.44 7.44 7.44 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database