CHEMBL3343983


SMILES COc1ccc2c(NCCCCCCCNc3ccnc4cc(OC)ccc34)ccnc2c1
InChIKey UZQGZSISQVAYCO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 444.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.46 7.46 7.46 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.64 6.64 6.64 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.59 6.59 6.59 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.55 5.55 5.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database