CHEMBL1075626


SMILES Clc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
InChIKey NBEFPXHBLZGXNK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 333.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 6.6 6.6 6.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pIC50 6.02 6.02 6.02 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pIC50 6.91 6.91 6.91 ChEMBL