Ligand Data
Ligand
| Name | CHEMBL3605290 |
| SMILES | Cn1c(C(=O)N2CCc3nc(COc4ccccc4)oc3C2)cc2ccccc21 |
| InChIKey | RMAIMPQJIXZAGX-UHFFFAOYSA-N |
| Type | small-molecule |
| External Links |
Structure
Properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 4 |
| Molecular weight | 387.2 |
Bioactivity
| Receptor | Affinity (nM) | Potency (nM) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Min | Avg | Max | Min | Avg | Max |
| mGlu5 | GRM5 | Human | Metabotropic glutamate | C (Glutamate) | 510 | 511 | 513 | |||