Ligand Data

Ligand

id 123229
Name CHEMBL3605290
SMILES Cn1c(C(=O)N2CCc3nc(COc4ccccc4)oc3C2)cc2ccccc21
InChIKey RMAIMPQJIXZAGX-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight 387.2


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
mGlu5 GRM5 Human Metabotropic glutamate C (Glutamate) 510 511 513