Ligand Data

Ligand

id 123238
Name CHEMBL3605300
SMILES CC1(C)CN(C(=O)c2ccc(F)cc2)Cc2oc(COc3ccccc3)nc21
InChIKey AMWBCTJDWPRVAG-UHFFFAOYSA-N
Type small-molecule
External Links

Structure

Properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight 380.2


Bioactivity

Receptor Affinity (nM) Potency (nM)
GTP Uniprot Species Family Class Min Avg Max Min Avg Max
mGlu5 GRM5 Human Metabotropic glutamate C (Glutamate) 170 172 174