CHEMBL3634813


SMILES Fc1ccc2c(C3CCN(CCCOc4ccc(-c5nc6ccccc6o5)cc4)CC3)noc2c1
InChIKey LKVJROOIPKZVDQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 471.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.12 6.12 6.12 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.73 6.73 6.73 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 7.27 7.27 7.27 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.66 7.66 7.66 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database