CHEMBL360716


SMILES CC(NC1CCCNC1)c1ccccc1N1CCN(C(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@H]2Cc3ccccc3CN2)CC1
InChIKey NKVAOVHVGQNSIX-CVZNUHMCSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 9
Molecular weight (Da) 628.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.82 5.82 5.82 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.57 6.57 6.57 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.7 5.7 5.7 ChEMBL
MC4 MC4R Human Melanocortin A pKi 8.19 8.19 8.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pEC50 8.33 8.38 8.42 ChEMBL