CHEMBL362542


SMILES Cc1cccc(NC(=O)CN2CCN(c3ccccc3C#N)CC2)c1
InChIKey IPAGYDFLTXLPDA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKd 8.4 8.4 8.4 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.84 8.34 8.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.12 8.12 8.12 ChEMBL