GproteinDb

dAVP

Agent/drug
Bioactivity

dAVP

SMILES	None
InChIKey	NFLWUMRGJYTJIN-UHFFFAOYSA-N
Sequence	XYFQNCPRG

Chemical Properties

Hydrogen bond acceptors	None
Hydrogen bond donors	None
Rotatable bonds	None
Molecular weight (Da)

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

OT	OXYR	Human	Vasopressin and oxytocin	A	pKi	6.70	7.73	7.60	Guide to Pharmacology
OT	OXYR	Rat	Vasopressin and oxytocin	A	pKi	9.01	9.01	9.01	ChEMBL
OT	OXYR	Human	Vasopressin and oxytocin	A	pKi	8.30	8.30	8.30	ChEMBL
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	7.00	7.88	7.70	Guide to Pharmacology
V_1A	V1AR	Rat	Vasopressin and oxytocin	A	pKi	5.60	5.60	5.60	Guide to Pharmacology
V_1A	V1AR	Human	Vasopressin and oxytocin	A	pKi	7.21	7.81	8.42	ChEMBL
V_1A	V1AR	Rat	Vasopressin and oxytocin	A	pKi	7.00	7.48	7.97	ChEMBL
V_1B	V1BR	Human	Vasopressin and oxytocin	A	pKi	7.70	8.38	9.40	Guide to Pharmacology
V_1B	V1BR	Human	Vasopressin and oxytocin	A	pKi	8.24	8.84	9.43	ChEMBL
V_1B	V1BR	Rat	Vasopressin and oxytocin	A	pKi	9.70	9.70	9.70	ChEMBL
V_1B	V1BR	Rat	Vasopressin and oxytocin	A	pKi	8.00	8.00	8.00	Guide to Pharmacology
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	7.20	8.10	8.60	Guide to Pharmacology
V₂	V2R	Rat	Vasopressin and oxytocin	A	pKi	8.70	8.70	8.70	Guide to Pharmacology
V₂	V2R	Human	Vasopressin and oxytocin	A	pKi	7.63	7.96	8.30	ChEMBL
V₂	V2R	Rat	Vasopressin and oxytocin	A	pKi	9.10	9.31	9.52	ChEMBL

Showing 1 to 15 of 15 entries

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Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

OT	OXYR	Human	Vasopressin and oxytocin	A	pEC50	6.96	7.05	7.14	ChEMBL
V_1B	V1BR	Human	Vasopressin and oxytocin	A	pEC50	7.96	7.96	7.96	ChEMBL
V₂	V2R	Human	Vasopressin and oxytocin	A	pEC50	9.70	9.70	9.70	ChEMBL
V₂	V2R	Rat	Vasopressin and oxytocin	A	pEC50	10.52	10.52	10.52	ChEMBL

Showing 1 to 4 of 4 entries

dAVP

Drug properties

Molecular type	Peptide
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 3

Phase II 12

Phase III 6

Phase IV 12

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids Guide To Pharmacology DrugBank ChEMBL_compound_ids PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease

Gene	Protein	Receptor family	Ligand type	Class	Name	Phase	ICD11	ATC	Association score

V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Central diabetes insipidus	4	5A61.5		0.566
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Enuresis, unspecified	4	6C00.Z		0.586
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Intracerebral haemorrhage, site unspecified	2	8B00.Z		0.092
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Leptospirosis	3	1B91		0.074
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of breast, unspecified	2	2C6Z		0.074
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of prostate, unspecified	1	2C82.Z		0.018
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Nasal congestion	4	MD11.9		0.565
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Overactive bladder	2	GC50.0		0.074
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Renal colic	3	MF56		0.259
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Superficial injury of unspecified body region	2	ND56.0		0.092
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Von Willebrand disease	4	3B12		0.462
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Central diabetes insipidus	4	5A61.5		0.566
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Enuresis, unspecified	4	6C00.Z		0.586
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Intracerebral haemorrhage, site unspecified	2	8B00.Z		0.092
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Leptospirosis	3	1B91		0.074
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of breast, unspecified	2	2C6Z		0.074
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of prostate, unspecified	1	2C82.Z		0.018
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Nasal congestion	4	MD11.9		0.565
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Overactive bladder	2	GC50.0		0.074
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Renal colic	3	MF56		0.259

Showing 1 to 20 of 33 entries

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Main reference

dAVP

dAVP

Chemical Properties

Database connections

Bioactivities

dAVP

Drug properties

Distribution across phases (no. indications)

Database connections

Sankey plot

Drug Information