CHEMBL3740256


SMILES O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCC(CN2CCC(c3noc4cc(F)ccc34)CC2)CC1
InChIKey LIHYUCWMNKTEOX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 525.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 7.36 7.36 7.36 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.49 7.49 7.49 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.66 7.66 7.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database