CHEMBL375504


SMILES Oc1ccc2c(c1)[C@]13CCN(CC4CCC4)[C@H](C2)[C@@H]1Cc1c([nH]c2ccccc12)C3
InChIKey OBRHLKNIVAKGEN-HUROMRQRSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 398.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 9.77 9.77 9.77 ChEMBL
κ OPRK Human Opioid A pKi 9.0 9.0 9.0 ChEMBL
μ OPRM Human Opioid A pKi 8.41 8.41 8.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 9.22 9.22 9.22 ChEMBL
δ OPRD Human Opioid A pEC50 9.1 9.1 9.1 ChEMBL
κ OPRK Human Opioid A pEC50 6.72 6.72 6.72 ChEMBL
μ OPRM Human Opioid A pEC50 6.96 6.96 6.96 ChEMBL