CHEMBL3770342


SMILES NC1=NC2(CCCCC2)NC(Nc2cccc(Br)c2)=N1
InChIKey DDIYHVZHGLOJAJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 1
Molecular weight (Da) 335.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.64 6.64 6.64 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.21 8.23 8.24 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.52 5.52 5.52 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.68 6.68 6.68 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.45 7.46 7.48 ChEMBL