CHEMBL3759292


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)NCC(=O)NCc1ccccc1
InChIKey SYOVEDOWOXNOJG-RRPNLBNLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 8
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pKd 9.15 9.2 9.25 ChEMBL
δ OPRD Human Opioid A pKi 9.8 9.81 9.82 ChEMBL
μ OPRM Human Opioid A pKi 7.79 9.15 10.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Mouse Opioid A pEC50 8.59 8.59 8.59 ChEMBL