CHEMBL3763717


SMILES Nc1nc(C(=O)NCc2cccc3cccnc23)c2ccc(F)cc2n1
InChIKey JHWYFIOMMXUNLT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 347.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 8.32 8.32 8.32 ChEMBL
A2A AA2AR Human Adenosine A pKi 9.52 9.52 9.52 ChEMBL
A1 AA1R Human Adenosine A pKi 7.51 7.51 7.51 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database