CHEMBL1196359


SMILES O=C(O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)[C@](O)(c1cccs1)C1CCCC1
InChIKey MTYMLJSBEPCLGC-ULIRXLGVSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 470.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.15 10.15 10.15 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 10.22 10.22 10.22 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 10.05 10.05 10.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M3 ACM3 Human Acetylcholine (muscarinic) A pIC50 9.74 9.74 9.74 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 9.85 9.85 9.85 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 9.82 9.82 9.82 ChEMBL