CHEMBL378859


SMILES O=C(NCCC1CCNCC1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1
InChIKey KXGAHULLQRZYOM-SXLOSVNLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 724.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 6.02 6.02 6.02 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.62 7.62 7.62 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.92 8.92 8.92 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.03 7.03 7.03 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.58 6.58 6.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database