GproteinDb

dexamfetamine

Agent/drug
Bioactivity

dexamfetamine

SMILES	C[C@H](N)Cc1ccccc1
InChIKey	KWTSXDURSIMDCE-QMMMGPOBSA-N

Chemical Properties

Hydrogen bond acceptors	1
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	135.1

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb
Structure pdb	8JSO

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₂	ADRB2	Human	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	8.29	8.29	8.29	Drug Central
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.18	5.18	5.18	PDSP Ki database
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₁	DRD1	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₂	DRD2	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₃	DRD3	Human	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database

Showing 1 to 7 of 7 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

TA₁	TAAR1	Human	Trace amine	A	pEC50	6.00	6.45	6.90	Guide to Pharmacology
TA₁	TAAR1	Rat	Trace amine	A	pEC50	6.10	6.25	6.40	Guide to Pharmacology
TA₁	TAAR1	Rat	Trace amine	A	pEC50	5.92	6.61	7.86	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pEC50	6.00	6.28	6.85	ChEMBL
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	6.66	7.50	8.70	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pEC50	8.16	8.16	8.16	Drug Central
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	8.06	8.06	8.06	Drug Central
TA₁	TAAR1	Rhesus macaque	Trace amine	A	pEC50	8.22	8.22	8.22	Drug Central
TA₁	TAAR1	Rat	Trace amine	A	pEC50	8.14	8.14	8.14	Drug Central
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	6.70	7.70	8.70	Guide to Pharmacology
TA₁	TAAR1	Rhesus macaque	Trace amine	A	pEC50	6.00	6.00	6.00	ChEMBL

Showing 1 to 11 of 11 entries

dexamfetamine

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

PubChem Guide To Pharmacology ChEMBL_compound_ids DrugBank Drug Central GPCRdb
Structure pdb	8JSO

Compound is not listed as a drug.