CHEMBL3819403


SMILES O=C(CCCCN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1nc2ccccc2s1
InChIKey MWVBXJPHOJRHOA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 9
Molecular weight (Da) 505.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.25 6.28 6.3 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.91 5.92 5.92 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.6 6.62 6.63 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database