CHEMBL3819494


SMILES c1ccc2c(c1)CCN(CCCCc1c[nH]c3ccccc13)C2
InChIKey PVACCLSEBPABQC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 304.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.28 7.29 7.29 ChEMBL
H1 HRH1 Human Histamine A pKi 6.08 6.08 6.08 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.77 5.77 5.77 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.03 6.03 6.03 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.33 6.33 6.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.77 6.79 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database