dexmedetomidine



dexmedetomidine


SMILES Cc1cccc([C@H](C)c2c[nH]cn2)c1C
InChIKey CUHVIMMYOGQXCV-NSHDSACASA-N

Chemical Properties

Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 200.1

Database connections

Structure pdb 7EJA 9CBM 6K42 6K41
Ligand site mutations α2A α2B

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

dexmedetomidine


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 12
Phase II 15
Phase III 30
Phase IV 6

Database connections

Structure pdb 7EJA 9CBM 6K42 6K41
Ligand site mutations α2A α2B

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score