CHEMBL384657


SMILES CC1(C)Cc2cccc(OCCNCc3cncc(C4=CCCC4)c3)c2O1
InChIKey XJUROKFTAHXDMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 364.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 9.56 9.56 9.56 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 9.02 9.02 9.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 8.54 8.54 8.54 ChEMBL