CHEMBL377050


SMILES CO/N=C(\CCN1CCN(c2ccccn2)CC1)c1ccccc1
InChIKey XGPLYCXGOOHULQ-DYTRJAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 324.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.64 7.64 7.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.76 6.76 6.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.5 7.5 7.5 ChEMBL