doxepin



doxepin


SMILES CN(C)CC/C=C1\c2ccccc2COc2ccccc21
InChIKey ODQWQRRAPPTVAG-GZTJUZNOSA-N

Chemical Properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 279.2

Database connections

Structure pdb 3RZE
Ligand site mutations H1

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

doxepin


Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 6
Phase III 4
Phase IV 14

Database connections

Structure pdb 3RZE
Ligand site mutations H1

Sankey plot

Drug Information

Target Disease
Gene Protein Receptor family Ligand type Class Name Phase ICD11 ATC Association score