CHEMBL393492


SMILES COc1ccccc1N1CCN(CCCCN2Cc3ccccc3C2=O)CC1
InChIKey DVYJEJMZLCRJNO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 6.86 6.99 7.12 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.52 7.52 7.52 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.5 6.98 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database