CHEMBL3818940


SMILES OC1(c2ccc(Cl)cc2)CCN(CCCCc2nc3ccccc3o2)CC1
InChIKey KGFWRFDEYGDLSQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 384.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.64 6.64 6.64 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.03 6.03 6.03 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.22 5.22 5.22 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.5 5.5 5.5 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.36 6.36 6.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database