CHEMBL3946540


SMILES Clc1cccc(OC[C@@H]2CN(CCN3CCc4ccccc43)CCO2)c1
InChIKey QAJBOIGVHPCSNX-FQEVSTJZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 372.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Mouse Adrenoceptors A pKi 5.04 5.04 5.04 ChEMBL
D3 DRD3 Mouse Dopamine A pKi 5.18 5.18 5.18 ChEMBL
D4 DRD4 Mouse Dopamine A pKi 6.84 6.84 6.84 ChEMBL
5-HT2B 5HT2B Mouse 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT1D 5HT1D Mouse 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pKi 6.26 6.26 6.26 ChEMBL
5-HT2A 5HT2A Mouse 5-Hydroxytryptamine A pKi 5.89 5.89 5.89 ChEMBL
α1B ADA1B Mouse Adrenoceptors A pKi 5.18 5.18 5.18 ChEMBL
D2 DRD2 Mouse Dopamine A pKi 5.72 5.72 5.72 ChEMBL
D1 DRD1 Mouse Dopamine A pKi 5.69 5.69 5.69 ChEMBL
α1D ADA1D Mouse Adrenoceptors A pKi 5.38 5.38 5.38 ChEMBL
5-HT2C 5HT2C Mouse 5-Hydroxytryptamine A pKi 5.47 5.47 5.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database