CHEMBL1207972
| SMILES | O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 |
| InChIKey | HJPAXYLYYQIFCK-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 6 |
| Molecular weight (Da) | 405.0 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| EP1 | PE2R1 | Mouse | Prostanoid | A | pKd | 7.32 | 7.32 | 7.32 | ChEMBL |
| EP2 | PE2R2 | Mouse | Prostanoid | A | pKi | 5.76 | 5.76 | 5.76 | ChEMBL |
| EP1 | PE2R1 | Human | Prostanoid | A | pKi | 8.1 | 8.1 | 8.1 | ChEMBL |
| EP1 | PE2R1 | Human | Prostanoid | A | pKd | 8.1 | 8.1 | 8.1 | ChEMBL |
| TP | TA2R | Human | Prostanoid | A | pKi | 8.0 | 8.0 | 8.0 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| EP1 | PE2R1 | Human | Prostanoid | A | pIC50 | 7.9 | 7.9 | 7.9 | ChEMBL |
| EP2 | PE2R2 | Human | Prostanoid | A | pIC50 | 5.8 | 5.8 | 5.8 | ChEMBL |
| EP3 | PE2R3 | Human | Prostanoid | A | pIC50 | 5.9 | 5.9 | 5.9 | ChEMBL |