CHEMBL3895047


SMILES CCC#CC[C@H](C)[C@H](O)/C=C/[C@H]1CC(F)(F)C(=O)N1CCc1ccc(C(=O)O)cc1
InChIKey NXJWISYZCAYZPY-XOWFKELMSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pKi 9.92 9.92 9.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Human Prostanoid A pEC50 5.79 5.79 5.79 ChEMBL
EP4 PE2R4 Human Prostanoid A pEC50 10.33 10.39 10.46 ChEMBL
EP4 PE2R4 Human Prostanoid A pIC50 9.49 9.49 9.49 ChEMBL