CHEMBL3970994


SMILES C1=C(CCN2CCc3ccccc3C2)CCc2ccccc21
InChIKey UXAXXXXPTUTANS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 289.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.85 6.85 6.85 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.18 7.19 7.19 ChEMBL
H1 HRH1 Human Histamine A pKi 5.84 5.84 5.84 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.54 5.54 5.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.86 6.86 6.86 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.01 6.01 6.01 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.73 6.74 6.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.25 5.25 5.25 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database