CHEMBL3986927


SMILES O=C1Cc2cc(C(=O)CCCN3CCc4ccccc4C3)ccc2N1
InChIKey GJUWVTJJMMQPAO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 5.48 5.48 5.48 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.9 6.9 6.9 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.32 6.32 6.32 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.37 5.37 5.37 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.91 6.91 6.91 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.99 5.99 5.99 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.18 7.18 7.18 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.27 5.27 5.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database