CHEMBL3990113


SMILES Clc1ccc2sc(CCCCN3CCc4ccccc4C3)nc2c1
InChIKey BTSMIVQFEUCDAW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 356.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 ChEMBL
H1 HRH1 Human Histamine A pKi 6.61 6.61 6.61 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.81 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.12 6.12 6.12 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.82 7.83 7.84 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.15 6.18 6.2 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.35 6.35 6.35 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.86 6.86 6.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database