CHEMBL3990611


SMILES Clc1ccc2sc(CCCCN3CCc4c(Cl)cccc4C3)nc2c1
InChIKey AJKOTVCMUKNUGM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 390.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 6.55 6.55 6.55 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 6.84 6.84 6.84 ChEMBL
H1 HRH1 Human Histamine A pKi 6.25 6.25 6.25 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.49 6.49 6.49 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.38 7.38 7.38 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.3 6.31 6.32 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.04 7.04 7.04 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.07 6.07 6.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database