CHEMBL392822


SMILES OC1(c2ccccc2Cl)CCN(Cc2c[nH]c3ccccc23)CC1
InChIKey UOVZXNPDZHFAHL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 340.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.55 5.55 5.55 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.73 5.73 5.73 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 6.23 6.23 6.23 ChEMBL