Chembl1222693

Chemical Properties

SMILES Cc1nc2n(c1C)Cc1ccccc1C=C2N1CCN(CC(C)(C)C(=O)O)CC1
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight 394.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey SOXIOTAVNTWQJT-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.2 7.2 7.2 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL