CHEMBL392991


SMILES COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccco4)cc13)CC2
InChIKey JXCCNCOVOMQXNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.8 6.8 6.8 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 8.1 8.1 8.1 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.69 6.69 6.69 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.69 6.69 6.69 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 8.1 8.1 8.1 PDSP Ki database
α2B ADA2B Human Adrenoceptors A pKi 6.8 6.8 6.8 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database