CHEMBL3986651


SMILES COc1cccc(OC[C@@H]2CN(CCN3CCc4ccccc43)CCO2)c1
InChIKey ROKNCKQMECSPFV-NRFANRHFSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 368.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Mouse Adrenoceptors A pKi 5.08 5.08 5.08 ChEMBL
D5 DRD5 Mouse Dopamine A pKi 5.07 5.07 5.07 ChEMBL
D3 DRD3 Mouse Dopamine A pKi 5.08 5.08 5.08 ChEMBL
α1D ADA1D Mouse Adrenoceptors A pKi 5.19 5.19 5.19 ChEMBL
5-HT2C 5HT2C Mouse 5-Hydroxytryptamine A pKi 5.42 5.42 5.42 ChEMBL
D4 DRD4 Mouse Dopamine A pKi 5.47 5.47 5.47 ChEMBL
5-HT2B 5HT2B Mouse 5-Hydroxytryptamine A pKi 6.18 6.18 6.18 ChEMBL
5-HT1D 5HT1D Mouse 5-Hydroxytryptamine A pKi 5.7 5.7 5.7 ChEMBL
D1 DRD1 Mouse Dopamine A pKi 5.08 5.08 5.08 ChEMBL
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pKi 6.76 6.76 6.76 ChEMBL
D2 DRD2 Mouse Dopamine A pKi 5.0 5.0 5.0 ChEMBL
5-HT2A 5HT2A Mouse 5-Hydroxytryptamine A pKi 5.85 5.85 5.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database