CHEMBL399164


SMILES CCCN(CCN1CCN(c2ccccc2OC)CC1)C1CCc2c(O)cccc2C1
InChIKey ZGSHIAJEAFZHNC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 423.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 7.73 8.54 9.34 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.05 7.51 8.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 10.1 10.1 10.1 ChEMBL
D2 DRD2 Human Dopamine A pEC50 8.81 8.81 8.81 ChEMBL