OXYMORPHINDOLE


SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2c2[nH]c4ccccc4c2C[C@@]3(O)[C@H]1C5
InChIKey YQNZUKAKYJMEFE-LMDOGRNLSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 0
Molecular weight (Da) 374.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pKi 5.66 5.66 5.66 ChEMBL
κ OPRK Mouse Opioid A pKi 7.11 7.11 7.11 ChEMBL
μ OPRM Mouse Opioid A pKi 6.18 6.18 6.18 ChEMBL
δ OPRD Mouse Opioid A pKi 9.1 9.1 9.1 ChEMBL
κ OPRK Guinea pig Opioid A pKi 5.35 5.61 6.4 ChEMBL
μ OPRM Rat Opioid A pKi 6.77 7.03 7.18 ChEMBL
δ OPRD Human Opioid A pKi 8.89 9.08 9.15 ChEMBL
κ OPRK Human Opioid A pKi 6.29 6.33 6.4 ChEMBL
μ OPRM Human Opioid A pKi 6.44 6.71 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database